By Dominic Toner

Tottenham have been installed as favourites to sign Isco as the possibility grows that he could leave Real Madrid by next weekend.

Spurs are rated as 3/1 favourites by SkyBet to land the 24-year-old midfielder before the transfer window shuts next Wednesday.

Italian duo AC Milan (8/1) and Juventus (12/1) are considered the next most likely clubs by the betting company to sign Isco, while Premier League rivals Arsenal and Chelsea are seen as outside bets at 20/1.

The betting update on Sunday comes after the Mirror reported that Spurs are keen on landing Isco on an initial loan deal until the end of the season.

It is said that the north Londoners would have the option to sign Isco on a permanent basis if his loan spell is successful at White Hart Lane.

Madrid completed the signing of Isco in 2013 when he moved to the Bernabeu from Malaga for £25million to work under previous manager Carlo Ancelotti.

Isco was a regular player under Ancelotti, making 106 of his 151 Real appearances for the new Bayern Munich boss.

The Spain international has a fine record at the Spanish giants, scoring 22 goals and supplying 35 assists in all competitions.

However, he has struggled under recent managers Rafa Benitez and Zinedine Zidane to land a starting role.

It is believed that current manager Zidane is under pressure to reduce the size of his squad and has opted to keep Colombian star James Rodriguez in favour of Isco.

Spurs have endured a mixed start to the Premier League season with one win and two draws, but the capture of Isco could help them challenge at the top of the table.

Isco’s high intensity and work rate seems well suited to Mauricio Pochettino’s style of football.

The midfielder has made 14 appearances for a highly competitive Spain squad, but could profit in the national team if given regular football.

Isco may be tempted by a move to White Hart Lane and experience his first taste of Premier League football.

In other Tottenham transfer news, they have offered £70,000-a-week to land a £20million forward by Wednesday.