Celtic are expected to recall Tom Rogic to the midfield and could make two changes to the side that triumphed last Friday.
Brendan Rodgers may be tempted to keep the same team that defeated Kilmarnock 1-0 in the Scottish Premiership although it is more likely he will make a couple of alternations.
Rogic could come into the side after missing out on the weekend due to a late return from international duty and he would likely replace Callum McGregor.
Dorus de Vries is also likely to come into the team as Rodgers is expected to give the reserve goalkeeper a run-out despite conceding seven goals in the first meeting between the sides.
The Hoops have enjoyed success in a 3-5-3 formation in the league and will be expected to keep the same back three which lined up against Kilmarnock in the hope of shutting out Neymar, Lionel Messi and Luis Suarez.
Mikael Lustig and Erik Sviatchenko are expected to be keep their places in the side while Dedryck Boyata should also retain his position after he was recalled against Kilmarnock.
The midfielders will be expected to play quite deep but Rodgers will hope his five men across the middle will squeeze out some of the space for Barcelona’s midfield maestros.
Patrick Roberts and Scott Sinclair are Celtic’s expected wingers, with Scott Brown and Stuart Armstrong likely to fulfill their usual roles in the centre of midfield alongside Rogic.
Moussa Dembele, who has already scored 16 goals in his first 25 appearances for Celtic, will likely partner Leigh Griffiths in attack as the duo have started to form a lethal partnership.
The duo are unlikely to get many chances, though Celtic have nothing to lose and should go into the game with positivity given their recent form in the Scottish Premiership.
In other Celtic news, this Scottish wonderkid trained with a different team ahead of his international debut.