Up to seven senior Tottenham stars are in line for late-window exits as the club try to partly fund their big summer spree, Football Insider understands.
Jose Mourinho has given the green light for multiple departures of those on the fringe of his team after telling the hierarchy the squad is now too bloated.
A Tottenham source has told Football Insider that the club are working to trim the wage bill as well as raise cash through sales.
A deal has already been agreed with Villarreal for Juan Foyth to join on an initial loan with a view to a £13.5million permanent move next summer.
Talks are also being held with various clubs over the permanent departures of full-back pair Danny Rose and Serge Aurier, centre-back Cameron Carter-Vickers and back-up goalkeeper Paulo Gazzaniga.
In addition, 2019 signings Ryan Sessegnon and Jack Clarke have been made available for loan.
Spurs wants significant loan fees for youngsters Sessegnon and Clarke, which is one reason why deals have not yet been agreed.
Of the seniors, Rose has been frozen out of the first-team squad this season and has been given the green light to leave if he can find a club.
Aurier has rejected a move to Spartak Moscow despite losing his starting place to summer signing Matt Doherty while Foyth is way down the centre-back pecking order.
Gazzaniga has slipped to third in the keeper pecking order following the arrival of Joe Hart, who has already started two games for the club.
Carte-Vickers has been the subject of bids from clubs including Bournemouth and Luton Town and could join a Championship side permanently.